WORKSHOP DESCRIPTION
Mechanical forces are integral to biological function, influencing multiple processes such as cellular adhesion, muscle function, and transport processes. From a molecular perspective, these cellular functions are underpinned by the activity of biomolecules that are mechanically stretched, and which conformational response to force determines their function. Studying such force-activated molecular processes cannot be approached with classic biochemistry techniques, requiring the implementation of single-molecule methods, that enable us to understand how typical biochemistry processes, such as molecular dynamics, binding interactions, or chemical modifications, are regulated by mechanical force.
In this workshop, hosted at Universidad Mayor, Santiago, Chile, we will explore the current experimental and theoretical approaches to understnad how mechanical forces influence biology at the molecular and cellular level. The workshop will include lectures from researchers working in the field of single-molecule force spectroscopy and mechanobiology, research talks, and practical sessions on experimental data analysis.